• cht18-60 manual

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    cht18-60 manual

    Pictures of the thermostat wiring is also helpful. How-to-insert-pictures But our problem started with water from our washer machine, and maybe the drain pan on the AC part of furnace. Also we not sure we have power to the 24vac, cause we do have power to the AC unit outside, and we got power to the furnace cause we testing with voltage meter and we got sparks by going too deep across metal breakers, and still got power now!Plenty to cause yourself serious injury. You need to check the control circuit. I’m not sure how your washing machine comes into play with your hvac problems.Can you post a few pics for us. I left you the link in my last reply. Many times we can see things in the pictures and we can direct you to them. A30-15 is only a partial model number.I got pictures but can't post. Do u have email address I could send them that way. Now if you want to, go to the website called Pins, look for Lowell dickerson user, click on furnace parts and you will see my furnace. Please write me back today!Do you have control voltage at the furnace. Do you have control voltage at the thermostat. Do you have control voltage at the condenser?How do you chech the one on the furnace?Check the primary and secondary side.List the primary and secondary voltages you found.Your either checking on the wrong terminals or your meter is screwed up. Check from R to C.Also from 6-9pm Eastern Standard Time, we have company, and he one of these people you can't work with cause he gets in the way, and he thinks he knows it all on anything you are trying to do or fix. Please write back but I talk after 9pm tonight!So are you saying you have a tech coming to look at your issue. Is this a handyman service or something. What significance did your washing machine play in all this. Was your furnace flooded?We thought it was coming from the washer, but apparently let was coming from the AC pan, in the furnace, cause each time we hear water running after the AC cut off.

    • goodman cht18-60 thermostat manual, cht18-60 manual, goodman cht18-60 manual.

    All these configurations can be The GMC thermostats that listed Always refer to the wiring diagram on the unit for the most up-to-date wiring. We can't connect to the server for this app or website at this time. There might be too much traffic or a configuration error. Try again later, or contact the app or website owner. They stop working yesterday evening. My dad and I checked both of them, and found one soft white wire in the Thermostat. Is that supposed to be like that. My problem is neither one is working, and we have electric to furnace, and AC unit out back is there anyone who can help us today. Please write me back soon!It sounds like you lost the 24vAC control voltage. You'd need a voltmeter and check it at the thermostat on the R and C terminals or at the air handler on the R and C wires.Now on the furnace, we have the 24vAC and the meter says it is working. We have electric at the furnace and on the AC unit out back and still not turn on. We tried crossing the R-W, R-Y, and R-G and we got nothing, no start no where. Can you help? The soft wire is on the thermostat from the circuit board to the temperature thing says.2 to 1.0! Please write me back soon, and thank you!It controls heat cycling. It has nothing to do with cooling. Check for a shorted low voltage wire to the outdoor unit. If you find the damaged wire and tape off the wires to prevent a short you will probably need to replace the low voltage fuse in the indoor unit.My furnace does not use any fuses. Please tell me where the low voltage wire is in my outside unit, and could it be the comparator on the fan in the furnace. Please write me back thank you!You said you confirmed the 24vac is working. You need to focus your attention to the air handler area. You may have a condensate overflow float that has tripped. It could be in the drain line or on the overflow pan. It's usually has two white wires connecting to it. A model number off the air handler (furnace) would be helpful.

    I wouldn't imagine the thermostat itself has gone bad already. Any help you can provide would be greatly appreciated, thanks in advance! The rebooting issue seems to be related to the Cooling unit. We welcome your comments andAll rights reserved. You may freely linkView our Privacy Policy here. The site may not work properly if you don't update your browser. If you do not update your browser, we suggest you visit old reddit. Press J to jump to the feed. Press question mark to learn the rest of the keyboard shortcuts Log in sign up User account menu 1 I want to change my archaic thermostat. What can I do with this wiring? What can I do with this wiring? It is a Goodman (GE?) CHT 18 60 and has a bunch of springs and a light bulb inside it for some reason. The only newer thermostat I know of that I can check compatibility is the Nest, I know some of you hate it, and it says incompatible. But I also have one blue wire that is not connected and I don't know if that will make a difference. So I'm hoping someone here can clear this up for me. Which thermostats can I install. I am hopefully looking for something similar to the nest if it is still incompatible. Any thermostat will work. Doesn't have to be nest. If you get the new Nest (2nd version), you don't have bring a common wire up to the thermostat. I only have heard people talking about that one recently so I just said that one since it seems the most advanced. I will have to look into the others and their features if I can swap it out and use any of them. I'm just tired of moving the dial 1mm and the temp shoots up 5-10 degrees. I can't even find the model number anywhere nor anything that looks like it on their website. Can you explain why the control board is needed.If you don't know how to do it, don't. You can end up with a fat bill if anything goes wrong.There is not one way to do it since all systems are different.

    We thought it was going into the pipe from the pan to outside the house, but it wasn't, in the floor. Well we got it all out, and the pan dry, and floor, and furnace too. And now the no work. But that don't explains the AC unit in the back, it was never wet, flooded or anything. The AC unit will not start either. But can you tell me where the R and C is in the Furnace. Please write back, and we are checking with a Volts, Ohms meters!Start with the transformer and work your way out, tracing power. If the furnace has no primary power, the transformer will not get power. Who is this person you said is going to look at the furnace.I'm still leaning towards a float switch.But still will not come on!Another member here offered to help you with pictures but you never sent them. What is a little wet. Did the control board get wet. Blower motor? Transformer?If your not comfortable with electrical work, is there someone you can call for help. It’s almost been a week and your still without a working unit. If the unit got wet, chances are you blew a fuse or breaker or caused unrepairable damage to the board. You could have also tripped a condensate overflow switch.It's been installed for several months with no problem, but I've recently been having trouble connecting through the iPhone app and the myinfinity website. My wall control shows my network status as connected to the SSID and the MyInfinity server, so I'm not sure what to do. Would love any insight here. Also, the wall control is working perfectly to control the system at the wall. It's just this remote access problem I'm encountering. Thank you. I'm a new homeowner, and I installed a Honeywell TH9320WF5003 thermostat in my house about 3 months ago. Everything has worked fine up until a couple of days ago. I go up to the thermostat and the screen is blank and nonresponsive. I can't seem to find any info out there about thermostats doing this, mostly it's posts about them not turning on at all.

    The installation instructions were generally easy to follow, but I also found additional information on the Honeywell website explaining what each terminal actually was. It would have been useful for Honeywell to print this in the instructions. Summarized: Rh: Heating power supply Rc: Cooling power supply W: Heating signal Y: Cooling signal G: Fan The two heating systems in my home are both ONLY heat, and have a two-wire connection. The wiring looked about a hundred years old, but still worked perfectly once I connected the wires to the Rh and W terminals. Interesting to note that in both installations it did not seem to make a difference which of the two wires went to what terminal, so long as it was Rh and W. However in a more complicated system that includes more wires for cooling or a fan, I'd use the included labels to mark each wire and be certain it was connected properly. I don't have any dollar amount savings to offer, but I can say that the temperature was MUCH more consistent in my apartment than it had been with the old round-style mercury switch which was prone to large temperature swings. There is no question in my mind that less fuel was used, and it's very likely that the two thermostats I purchased have already paid for themselves one month later. I love it! I used to worry that my HVAC equipment could be damaged if the mercury ball bounced on closing. No more problem! Setting the temperature used to be vague. No more problem! I used to get chilly waiting for the heat to come on and hot waiting for it to shut off. No more problem! In the cooling season, the mercury thermostat would call for progressively lower temperatures after it was turned on. No more problem! Restarting a compressor too soon could damage it. No more worry! Connecting the wires was unexpectedly troublesome. I straightened the ends with my fingers, stuck them in the terminals, and tightened. I couldn't get them really secure until I used pliers to get the ends really straight.

    Also, the wiring with the electrical tape covering could also be the issue if the wires are broken internally (most t-stat cable is solid wire), it will intermittently short on and off whatever that wire is controlling. Not for any actual exchange or installation of a new one. Depending on what thermostat I end up getting I will probably call one to make sure everything is done correctly. Just not that one. Thanks for clearing up what that bulb was. I had never saw a thermostat with one of those before, are those still common. Most wires will go to the same location but it is always good practice. Also male sure to have the thermostat wired and set(sometimes you have a switch) for your type of furnace ie gas, electric, etc. There's nothing ready-to-go, but you can use some of my code if it's helpful (probably going to do some kind of GPL or AGPL license on it). Right now, it only supports running on an actual Nest, or reading a HTU21D temperature sensor, but it should be simple to extend while taking advantage of the same thermostat logic. All rights reserved Back to top. To calculate the overall star rating and percentage breakdown by star, we don’t use a simple average. Instead, our system considers things like how recent a review is and if the reviewer bought the item on Amazon. It also analyzes reviews to verify trustworthiness. See All Buying Options Add to Wish List Disabling it will result in some disabled or missing features. You can still see all customer reviews for the product. Installation of both models is identical, and the main difference between the two is just the ability to set up a program of varying temperature changes based on your schedule. The non-programmable RTH111B has no clock feature. Just simple buttons to change the temperature up or down, and switches for a system fan (if applicable) and the HEAT-OFF-COOL selection. The apartment that received the RTH111B is a simple heat-only gas powered baseboard system.

    Kindle Customer 3.0 out of 5 stars I compared the temperature reading with other thermometers however, and it is off by 1.2 degrees as I write this. I can just take that into account and adjust the temperature for comfort but it would be nice if it were more accurate. Also, a suggestion for the manufacturer would be to include a bezel to cover the area of the wall that was covered by the thermostat being replaced. I will need to do some painting around this device because it is a little smaller than the one I had in place before.Please try again later. Please try again later. Daine P 5.0 out of 5 stars We have very odd home hours and have found that the very snazzy programmable thermostats really don't work for us so I went as simple as possible. We were very happy with the fist one so I bought a second to replace the remaining old thermostat. All good.Please try again later. Please try again later. Jeff 4.0 out of 5 stars Nice two piece design makes it easy to wire up and attach to the wall, then you snap the actual cover over it. I have this controlling a 45k BTU Garage furnace. Has worked well for about a month so far. Digital readout makes it easier to fine tune your setting, also has a low 40 degree setting which I haven't seen in a mechanical thermostat. Can easily change between Fahrenheit and Celsius if you want to (read directions, involves holding both buttons down for 5 seconds).Please try again later. Please try again later. D. Salotti 3.0 out of 5 stars It seems to be reliable within 2 degrees -- it often overshoots the heat by about that much before kicking off. That aside, it functions as it should and handles both heat and cooling.Please try again later. Please try again later. Barry J Martin 5.0 out of 5 stars Please try again later. Please try again later. See More cugoodman2-5 Published on Oct 17, 2011 50 Hz This 50-Hz split system air conditioner allows for ground-level or rooftop applications and has been tested for optimum performance by.

    Page Count: 4 Standard FeaturesLaboratories, Inc., per ARI Standard 210-240AccessoriesElectrical. Unit TypeIndoor UnitSensibleCompressorCondenser Fan Motor. HorsepowerRefrigeration System. Liquid Valve Size (“O.D.). Suction Valve Size (“O.D.). Valve Type. Refrigerant Charge. Shipped with Orifice Size. Horsepower - RPM. Outdoor Nominal CFM. Face Area (ft?). Fin Type. Coil No. of Tubes. Coil Tube Diameter (in.). Electrical Data. Min. Circuit Ampacity? Max. Overcurrent Protection (amps)? Power Supply Conduit SizeExtensive wire runs will require larger wire sizes.Depth. HeightLow-Voltage Circuit. Component Legend. C - Contactor. Comp - Compressor. FC - Fan Motor Capacitor. HP - High-pressure Control. FM - Fan Motor. IO - Internal Overload. Single-Phase Line Voltage. Quality Makes the Difference! All of our systems are designed and manufactured with the same high-quality standards, regardless of size or efficiency. We have designed these units to significantly reduceThey are simple to service and forgiving to operate. We use quality materials and components. Finally, every unit is run-testedThat’s why we know. there’s no better quality. Visit our website atGoodman Manufacturing Company, L.P.Houston, Texas 77092 USA. Goodman Manufacturing Company, L.P., reserves the right to discontinue, or change at any time, specifications or designs without notice or without incurring obligations.File Type Extension: pdf. PDF Version: 1.4. Linearized: Yes. Page Count: 4. XMP Toolkit: XMP toolkit 2.9.1-13, framework 1.6. About: uuid:5853a47f-fe94-43f0-9b1b-b1f7126fdfae. Producer: Acrobat Distiller 6.0 (Windows). Create Date: 2006:11:28 07:48:05-06:00. Creator Tool: PScript5.dll Version 5.2. Modify Date: 2006:11:28 07:48:05-06:00. Document ID: uuid:35d564c8-2829-4952-8323-8e6689b97271. Title: SS-CKF50.indd. Creator: GMCHOU1CLS. Author: GMCHOU1CLS.

    The job would have been easier if the instructions had specified the best screwdriver and mentioned getting the wire ends really straight. If you shut off the thermostat while you're away or to remove it, it's important to see if it's switched to Cool, Off, or Heat. The print was so small and pale that I had to turn on a light and get my glasses. I cut out the little square of paper, applied it to the thermostat with clear tape, and blackened the switch with a magic marker. Now I can see how it's set from across the room in low light. Update: Early in the fourth heating season, I saw the furnace cut off while the thermostat was still calling for heat. I couldn't find a reason, and I couldn't repeat it. The chimney blower comes on for perhaps 40 seconds before the burner lights. Late in the season, I heard the blower cut off twice during those 40 seconds. I removed the thermostat and with a multimeter found erratic resistance between the red terminal and the white one when the relay clicked. Whether it was the relay, the slider switch, or something else, the thermostat proved unreliable. Please try again later. From the United StatesI also purchased the similar Installation of both models is identical, and the main difference between the two is just the ability to set up a program of varying temperature changes based on your schedule. There is no question in my mind that less fuel was used, and it's very likely that the two thermostats I purchased have already paid for themselves one month later.Please try again later. Please try again later. Stephen Throop 1.0 out of 5 stars No more problem! Setting the temperature used to be vague. Whether it was the relay, the slider switch, or something else, the thermostat proved unreliable.Please try again later. Please try again later. Lorax 2.0 out of 5 stars The way it is made the cover sometimes has to be twisted for it's weird wire connections on the inside and then it will work for awhile with no problems.

    Suddenly it doesn't work and we have to twist the cover again to make it work. This has been going on for about 2 years. This is the second thermostat control I've bought since I bought my house (the first one was worse) and I don't want to keep putting good money into bad products. I feel that simple products like this should last 20 years and not need to be played with all of the time to keep it working. It is very much not worth the money.Please try again later. Please try again later. GROG 5.0 out of 5 stars You will also need two AAA batteries. We did not time the installation but it took us much less than an hour. (Note: one of us is way above average mechanically and is a experienced DIY for mechanical, electrical and plumbing projects around the house and vehicles) After installation we tested the unit and it worked perfectly for heating and cooling as well as manual fan operation. For us all the controls are straight forward to use. Our HVAC system consists of a split central air-conditioner for cooling and strip heaters in the ducting for heating. (Not a heat pump) We saw no need for a fancier programmable unit. So far the unit has provided the desired ease in setting and precision in maintaining temperature.Please try again later. Please try again later. Bob-O-Link 5.0 out of 5 stars I purchased and moved to a new-to-me house in November with an ancient natural gas forced-air furnace system that still had one of the old round, spring loaded mercury switches. I pulled the cover off and the whole thing fell apart in my hands. LOL. I plan to buy a new, much more efficient furnace in a few months, but in the meantime needed a thermostat to get us through the winter. So far, this thermostat is working well. It was easy to install and set-up. The temperature appears to be 2-3 degrees off from other thermometers we have, but no biggie.At least it is consistent. I am very happy with this product. Recommended.Please try again later. Please try again later.


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  • cht-8q manual

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    cht-8q manual

    With larger speakers, you might start with this control set lower, such as 70 Hz. Subwoofer Direct Subwoofer Direct is a setting on the low-pass crossover knob and will allow frequencies up to 120 Hz into the subwoofer. See below for a more detailed explanation of this feature Figure 3. CHT-15Q Rear Panel Connections 8 - CHT-Q Series User’s Manual www.velodyne.com. In some rare cases, combining both an external crossover and the one internal to the subwoofer may result in low output and increased noise. There are many high quality cables available today. It is recommended that you keep the length of cable as short as possible to avoid any potential noise problems. The presets provide the following characteristics for bass reproduction: Movies: Maximum output and impact for explosions and other action adventure movie content. The flattest frequency response of the four presets. Games: Maximum loudness available for the impact of video games. www.velodyne.com CHT-Q Series User’s Manual - 13. CARE OF YOUR SUBWOOFER your Velodyne subwoofer does not require any regular maintenance.Abrasives, detergents, or cleaning solutions may damage the finish on the cabinet. We. If the protection circuitry is active, the unit may cycle on and off until operating parameters return to normal. Under more serious conditions, the unit may shut off completely. Normal operation should return upon cooling, but you may be required to turn the power off and then on again to reset the unit. The following conditions require service by a qualified technician: 1. The power cord has become damaged 2. The unit does not appear to operate normally or exhibits a marked change in performance 3. The unit has been exposed to water 4. Some part of the chassis or circuitry is physically damaged Thank You for Purchasing a Velodyne CHT-Q Series Subwoofer Product! 16 - CHT-Q Series User’s Manual www.velodyne.com.

    • velodyne cht-8q manual, velodyne cht-8q service manual, cht-8q manual.

    Congratulations on your purchase of a Velodyne CHT-Q subwoofer. This system represents the. Your new Velodyne subwoofer provides for a number of installation options. Read all of the. InputsSee below for a. Both sets of inputs sum the left and right channels together and the resulting signal is passedWhen installing your new Velodyne subwoofer using the line level connections, you should. Our passion for high performance, low-distortion bass is the driving force behind our worldwide reputation in audio and technical innovation. We are pleased to bring the Velodyne sound experience to your home. To avoid electrical shock, do not open the speaker enclosure or amp chassis cover. Please observe all warnings on the equipment itself. There are no user serviceable parts inside. Please refer all service questions to your authorized Velodyne dealer. Prior to Installation: Please unpack the system carefully. Should you find it necessary to use it with an older CRT monitor or TV, keep it at least two feet from the monitor. Experiment for correct distance by minimizing distortion of the picture and colors. The default crossover setting is 80 Hz. With larger speakers, you may want to set this even lower, for example 70 Hz. To adjust, simply listen to www.velodyne.com CHT-Q Series User’s Manual - 3. To correct this, see the VOLUME CONTROL section on previous page. 4 - CHT-Q Series User’s Manual www.velodyne.com. If you use this method of connection, when you go to the receiver speaker set up menu, make sure you select the large speaker option. 6 - CHT-Q Series User’s Manual www.velodyne.com. Rear Panel Connections — Detailed Explanation Your new subwoofer is equipped with both speaker-level and line-level inputs. The “SPEAKER LEVEL INPUT” jacks connect directly to the speaker outputs of an integrated amplifier or receiver. Your amplifier section will notice no additional loading effects when you use these inputs because of their high impedance.

    Keep in mind that frequency response and output level can be drastically influenced by placement, depending on the acoustic properties of the listening room. Typically, the optimum location for a subwoofer is tucked away in a corner of your list. If you use this method of connection, when you go to the receiver speaker set up menu, make sure you select the large speaker option. We can't connect to the server for this app or website at this time. There might be too much traffic or a configuration error. Try again later, or contact the app or website owner. Transfer”, enter the extension or name. Open the app on your device, tap on the menu (top left) and then “Scan QR Code”. In the Web Client, activate the extension and you’re all set. Disable and remove the 3CX Click to Call Extension if you have it installed. Learn More To Transfer a Call: Click “Transfer” or “Att. Transfer”. Enter the extension or search by name, tap “Transfer” and hang up. On-Premise, Your Cloud or Hosted By continuing to use our site, you agree to our use of cookies. OK. Credits are also nowThis includes theYes, we cheat on preparing the selector list.Hope this is useful to someone. Rather, it is important to extract the contents within the and tags only. If you are an existing customer, you need to opt in from your preferences. Provide feedback of the new GoToMeeting experience here. Log in to your account at. Click Settings in the left manu and New Experience. The next time you host or join a meeting, you will run the New GoToMeeting. If you'd like to go back to the previous version of GoToMeeting, click here. Click the Settings icon to switch audio modes or devices. Select Computer to use your computer's mic and speakers. Select Phone to use your telephone to dial in to the audio conference or to have GoToMeeting call you. Your Audio icon glows green when you are unmuted and red when you are muted. Learn more. You can switch between Computer and Phone audio by clicking the Settings icon.

    If you purchased your product outside of the United States or Canada, please consult your local authorized Velodyne dealer for warranty registration and information. www.velodyne.com. No user-serviceable parts inside. Refer servicing to qualified service personnel. The exclamation point symbol is intended to alert the userThis system represents the state of the art in low frequency reproduction. Read and follow the instructions below to insure safe and proper system operation. Warning! To prevent fire or shock hazard, do not expose this equipment to rain or moisture. To avoid electrical shock, do not open speaker enclosure or amp chassis cover. There are no user serviceable pRead all the installation information below in order to determine which installation option is best for your system. Remember to perform all installation procedures with system power turned off. Inputs Your new subwoofer is equipped with both speaker-level and line-level inputs.If you are not using an external crossover, we recommend that you use the one provided within the unit for optimum performance. To adjust, simply listen to the system with musBy utilizing this method, you will have a bi-amplified system, gaining improved power and headroom for your system. Figure 1: InstallIn some installations, it may be beneficial to have a steeper ultimate crossover slope. To do this you can use both your processor's crossover and the one internal to the Velodyne sub. You should stagger the frequencies (i.e., 120Hz sub, 80Hz processor) for best results. To bypass the subwoofer's internal crossover when the unit is being fed a low pass signal from another crossoverRed (positive) to red, and black (negative) to black. Be sure that all connections are tight, and that there are no loose strands or frayed wires.While it is recommended that the subwoofers be placed on the same plane as the satellite speakers, room and system conditions often dictate otherwise.

    That means you no longer have to worry about being disrupted by additional attendees if the session goes over the scheduled time and you have back to back meetings. The Lock icon will close, and you'll be notified when an attendee attempts to join your session. The Lock icon will switch to an open lock. To access the drop-down menu, click GoToMeeting at the top of the Viewer or Control Panel. See here for more information. Your feedback helps us improve the experience of GoToMeeting and allows us to understand how we can make GoToMeeting more user centric. Please provide your feedback here. Thank you! If you're an attendee, see our Attendee User Guide.We urge you to try our support articles and tutorials before you call. We urge you to try our support articles and tutorials before you call. Invariant Sections, with no Front-Cover Texts, and with no Back-Cover. Texts. A copy of the license is included in the section entitledThis allows you to start a retrievalThis is sometimes referred toWget can read the time-stampIf the serverWget uses the passiveIPv4-only and dual family environments.Interactive downloads are tracked using a “thermometer”-style gauge,Wget allows you to define global startup files. You can alsoThis means that everyone may use. Public License, as published by the Free Software Foundation (see theThe basic syntax is:Wget. You can do it two ways: permanently, adding the appropriateWget recognizes the URL syntax as perOn multi-user systems,To work around it, use wget -i - Long options areYou may freelySo the following will try to downloadThis can be useful toAll such options share severalFor example, theBut the startup file may in fact changeIf no output file isThe messages are normally reportedYour systemPlease note that compiling withThe default outputFurthermore, the file ’s location will be implicitly used as baseMetalink version 3It appends.badhashThen it switches to Metalink download.

    Click the Arrow icon next to any participant's name to see all options, including the following: Mute their audio Promote them to Presenter or Co-organizer Allow them to take keyboard and mouse control You can easily find and copy these meeting details to send. Click the People icon. At the bottom of the People pane, click Copy Meeting Link. This will copy the join URL to your clipboard, making it easy for you to paste anywhere. At the bottom of the People pane, click Invite People.Learn more. Do you want to preview your camera first. Click the Settings icon. You will instantly see a preview of your camera feed. Click the Camera Feed drop-down menu in the Viewer or Control Panel and Hide Everyone. Access the GoToMeeting Preferences and click Webcam in the left menu.You can undock the camera feeds from your Viewer window and move them independently around your screen by clicking the Undock icon in the side toolbar of the Viewer.Use the Screen button in the Viewer or Control Panel to quickly start and stop sharing your screen. Learn more. You'll be notified if you receive a chat and your Chat pane is minimized. Use the Send To drop-down menu to select your recipients: Everyone - Send a message to all meeting attendees Organizer(s) only - Send a message only to organizers and co-organizers. Specific attendee - Send a private message to just that person. You can save a.RTF file of the chat log by clicking GoToMeeting in the top menu and Save Chat Log. When prompted, select a place on your computer to save the file and click Save. This allows you to easily share past meetings with others. Learn more. Click the Record icon on the Viewer or the Control Panel. Access your recording in the following places: If you're recording to the cloud, find your recording in your web account. If you're recording locally, the Recording Manager will automatically prompt you to convert the recording.

    ThisUse of this option is discouraged, unless you really know what you areOther than that, they work in exactly the same way. In particular,Wget does not currently support. Only one ofMost servers however expectAny other controlIt’s not quite clear how to work around this limitation inherent inIn case a server wants the client to change the Request method uponMethod to the server.Other than that,Please be aware that Wget needs to know the contents ofAnother exception is whenThis can currently result inBy default the local file name is based onSupply a comma-separated list of 3-digit HTTP response codes asRetries enabled by this option are performedWget.Please use wiselyThe current default is GnuTLS. In addition, Wget also supports HSTS (HTTP Strict Transport Security). If Wget is compiled without SSL support, none of these options are available.This is the default.Fortunately, such servers are quite rare.In short, PFS adds security by creating a one-timeIt has a bit more CPU impact on client and server. We use known to be secure ciphers (e.g. no MD4) and the TLS protocol. This modeTypically this string sets theThis stringWget will not process or manipulate itAlthough this provides more secure downloads, it does breakThis option forces an “insecure” mode ofIf you are really sure of not desiring any certificate verification, youThis is needed forNormally a certificate is not required and thisLegal values areThis allows you to provide theThe certificates must be in PEM format.This is achieved by processing aThis is needed for certificatesThis can be a path to a file which contains a single public key in PEM or DERA public key is extracted from this certificate and ifEGD stands for Entropy. Gathering Daemon, a user-space program that collects data fromEncryption software, such as the SSLIf this variable is unset, orEGD is not needed on modern UnixSuch file must conform to theIf Wget cannot parse the providedEach line contains an HSTS entryLines starting with.

    Please note that in spite of this convenientThe port field may be zero, and it will, inWhen port is different to zero, both theApplying HSTS policies to ports. Thus, this functionality should not be usedThe last three fieldsThe created and max-age fieldsHSTS-defined value ’max-age’, which states how long should that HSTS policy remain active,Once that timeWhen Wget exists,This file will contain the new HSTSBefore dumping the updated HSTS entriesIf the passwords areNot removing them can be useful forDepending onA user could doGlobbing refers to the use of shell-likePassive FTPBehind most firewall and NATSymbolic links are always traversed in thisImplicit FTPS consists of initializing. This option does not sendImplicit FTPS is no longer a requirement for FTPS implementations, and thusTypically, the FTPS servers want it that way,Under rare circumstances however, one might want toOnly the control connection will beFor security reasons,The default behaviour is to exit with an error. If a server does not successfully reply to the initial AUTH TLS command, or in theSee Recursive Download, for moreIt is useful for pre-fetching popularThis affects not only the visibleThe fact that the former links are convertedThis filename part is sometimes referred to as theIt proves useful to populate Internet cachesThis option turns on recursionThis includes such things asAs you can see, 3.html isHowever, with this command:To download a single HTML Links from thatActually, to downloadThe default is to terminateBeginning withNote that ifIn this case, you have to enclose the pattern into quotes to preventWithout this option. Wget will ignore all the FTP links.One can’t just tell Wget toNow the best bet for downloading a single page and its requisites is theThis influences theFor example, with this.

    If no valid Metalink metadata is found, it falls back to ordinary HTTP download.This has effect if multipleThis is equivalent to theIPs.If you ever need toWget needs to be built with libcares for this option to be available.Wget needs to be built with libcares for this option to be available.A warning will beThis was disabled in versionSuch backupThis is useful when youThis is the default behavior.The same happens when the fileThis behavior canYou need to be especiallyIn the future aOffset may be expressedIt draws an ASCII progressThe parametersParameters to type are passed byDifferent styles assignWith the default style each dotThe binary style has a more “computer”-like orientation—8KIf mega is not enough then you can use the giga In certain cases, such as withSee Time-Stamping, for details.This allows the use of. However, itThis is equivalentThis prevents anomaliesThe only timeout enabled bySetting a timeout to 0 disablesSubsecond timeouts are useful for checkingDNS lookups thatBy default, thereTCP connections thatBy default, there is noThis optionThe default read timeout is 900However, it may take someInstead of in seconds, the time can beThis option causes the time between requestsIts author suggested blocking at the class C address level to ensureWget.The value can beThe same goes even when severalHowever, quota isNormally, Wget remembers the IPWith this option Wget issues aPlease noteCharacters that are restricted This option is useful forThis option may make senseThis can be useful when saving filenamesBy default, an IPv6-aware. Wget will use the address family specified by the host’s DNS record. If the DNS responds with both IPv4 and IPv6 addresses, Wget will tryIPv6 address families on dual family systems, usually to aid debuggingOnly one ofThe address order returned by. DNS is used without change by default.

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    The quotes in the example are to prevent the shell from expanding theUseful for retrieving a specific home pageElements ofThis is a useful option, since it guarantees that only the filesSee Directory-Based Limits, for more details.Recursive downloads would virtually alwaysWe refer to this as to recursive retrieval, or recursion.In other words, Wget firstThe default maximum depth is five layers.It is also useful for WWW If downloadingIf you wantIf you want to download allSee Following Links, for more informationDon’t say you were notThis is a reasonableMaybe you’re mirroring a site that consists of pages interlinked betweenUnless sufficientFor example, if you areEach optionLook up the manual of your shell forAnalogously, to download all files except the ones beginning with. The quotes are to preventIt is expected thatThe rationale was that, sinceThere can be many reasons for this—theSupposing you issue Wget with:HTTP has no concept of a “directory”—WgetIn simple cases it also allows downloadsHaving done that, FTP. This is logical,On the other hand, domain acceptanceInternet is updating your archives.This is why all the mirroring toolsWe call this information theWget will check whether a local file of the same name exists. If itSay you would like to download aAs you can see, the time-stamping info is preserved locally, evenIf the local fileHowever, if the remote file is more recent. Wget will proceed to fetch it.For example:For FTP, this depends on getting aIf you wish to retrieve the fileIf the remote fileIt will try to analyze the listing,The rest is exactly the same as for HTTP. Note that whenBear in mind that RFC959 We can only hope that a future standard will define this.Wget may support this command in the future.You can do that in a convenient way by creating the Wget startupIf the environmental variableFailing that, noFascist admins, away!Legal values are listedCannot be specifiedBackups are rotated by.

    The default isThe same asThe same asThe same asThe default is “on”. The same asEquivalent toYou can postfix the value withThe same asWithout this setting, theThe same asYou can put thisAvailable only if Wget was compiled with IPv6Available only if. Wget was compiled with IPv6 support.The same asThe address order returned by. DNS is used without change by default.The same asThe same as See Robot Exclusion, for moreNote that this isIt is divided in two section—one for global usage (suitable for globalFor a command to haveYou can find this here. The default is 5. However, some. If you are in suchAccept-Language. Valid options are default. Set this toThe connection will probably fail before the whole file is retrieved,Wget will take care of login andAlso make sure the downloaded pageIt would be:You can put Wget in the crontab file asking itWget invocationOne typical use of proxiesWhen a cached resource isAnother use forIn order to obtainFor instance, if the value ofFor proxy authorization only theAssuming that theFor example. Wget 1.20 can be found atGmane archives conveniently include messages from both the currentMessages also show up in the GmaneWget crashes, it’s a bug. If Wget does not behave as documented,Only if it turns out thatIf Wget was compiled withoutHowever, since itIf Wget fails to compile on yourUnix, but it should work as a substitute for people stuck with. Windows. Note that Windows-specific portions of Wget are notAll questions and problems in. Windows usage should be reported to Wget mailing list at. Windows-related features might look at them.Vanem; a port to VMS is maintained by Steven Schweda, and is availableIf the output was on standardOtherwise, SIGHUP is ignored. This is convenient when you wishA site I know has aHowever, when someone’s recursive WgetThe idea is thatBecause of that, Wget honors RES whenFor instance, when you issue:Wget has supported the additional directives specified in the internet. Robots Control”.

    The draft, which has as far as I know never made toHere are theWget’s standard input, each on a separate line, terminated by C-d. Another workaround is to use.netrc to store passwords; however,There is no goodKacar—feature suggestions and “philosophical” discussions.Maintained GNUWindows and MS-DOS support.Notably, conversion of Wget to use the Gnulib quotes and quoteargsGnulib getpasswd-gnu module.Adrian Aichner. Martin Baehr. Dieter Baron. Roger Beeman. Dan Berger. T. Bharath. Christian Biere. Paul Bludov. Daniel Bodea. Mark Boyns. John Burden. Julien Buty. Wanderlei Cavassin. Gilles Cedoc. Tim Charron. Noel Cragg. Kristijan Conkas. John Daily. Andreas Damm. Ahmon Dancy. Andrew Davison. Bertrand Demiddelaer. Alexander Dergachev. Andrew Deryabin. Ulrich Drepper. Marc Duponcheel. Damir Dzeko. Alan Eldridge. Hans-Andreas Engel. Aleksandar Erkalovic. Andy Eskilsson. Joao Ferreira. Christian Fraenkel. David Fritz. Mike Frysinger. Charles C. Fu. FUJISHIMA Satsuki. Masashi Fujita. Howard Gayle. Marcel Gerrits. Lemble Gregory. Hans Grobler. Alain Guibert. Mathieu Guillaume. Aaron Hawley. Jochen Hein. Karl Heuer. Madhusudan Hosaagrahara. HIROSE Masaaki. Ulf Harnhammar. Gregor Hoffleit. Erik Magnus Hulthen. Richard Huveneers. Jonas Jensen. Larry Jones. Simon Josefsson. Mario Juric. Hack Kampbjorn. Const Kaplinsky. Goran Kezunovic. Igor Khristophorov. Robert Kleine. KOJIMA Haime. Fila Kolodny. Alexander Kourakos. Martin Kraemer. Sami Krank. Jay Krell,Christian Lackas. Hrvoje Lacko. Daniel S. Lewart. Nicolas Lichtmeier. Dave Love. Alexander V. Lukyanov. Thomas Lu?nig. Andre Majorel. Aurelien Marchand. Matthew J. Mellon. Jordan Mendelson. Ted Mielczarek. Robert Millan. Lin Zhe Min. Jan Minar. Tim Mooney. Keith Moore. Adam D. Moss. Simon Munton. Charlie Negyesi. R. K. Owen. Jim Paris. Kenny Parnell. Leonid Petrov. Simone Piunno. Andrew Pollock. Steve Pothier. Jan Prikryl. Marin Purgar. Csaba Raduly. Keith Refson. Bill Richardson. Tyler Riddle. Tobias Ringstrom.

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    Fc retention was dominated by calcium affinity, while retention of Fab was dominated by cation exchange. The retention curve for intact IgG incorporated the distinctive elements of its fragments but stronger retention than that predicted by their addition to one another. Aggregate retention paralleled the curve for non-aggregated antibody, with stronger retention by both binding mechanisms. Experimental data revealed evidence of charge repulsion between IgG carboxyls and HA phosphate at low conductivity values. Electrostatic repulsion of amino residues and attraction of carboxyls by HA calcium appeared to be blocked by strong complexation of calcium with mobile phase phosphate. In addition to the economic value of these applications, the well-characterized structures of IgG and related entities make them suitable probes to investigate the surface reactivity of HA. The above studies, reporting on about 20 IgG monoclonal antibodies, have demonstrated that IgG is retained dominantly by a combination of calcium metal affinity and phosphoryl cation exchange, regardless of subclass, light chain type, or p I. These studies have also contributed important refinements to our understanding of IgG interactions with HA. A number of interactions predicted by studies on peptide and protein models remain uncharacterized. HA phosphates may repel protein carboxyls, in addition to their documented ability to bind amino groups. Dissecting the individual influence of these potential interactions is complicated by the arrangement of calcium and phosphate on the crystal surface. Cooperativity is described as positive in cases where multimodal interactions produce progressively stronger binding and negative where interactions depress net retention. Open in a separate window Figure 1 Distribution of charges on the crystal surface of HA. The parallelogram represents a portion of the crystal surface perpendicular to its longitudinal axis.

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    If subjected to mechanical shear, CHT media particles can fracture, creating fines. This article describes straightforward best practices for successful and reproducible CHT media column packing at process scale. Register today. Hercules, CA 94547Learn more. CHT ceramic hydroxyapatite overcomes the physical and chemical limitations of traditional crystalline hydroxyapatite and provides the throughput, stability, and reproducibility required for industrial biopharmaceutical manufacturing. CHT ceramic hydroxyapatite is a chemically pure form of hydroxyapatite that has been sintered at high temperatures to yield a physically and chemically robust support. It possesses high protein binding capacities and can be used reproducibly for hundreds of cycles in large columns run at high flow rates. Both types retain the separation properties of crystalline hydroxyapatite as well as possessing some unique properties of their own. Type I CHT has a higher protein binding capacity than Type II, and in particular, a higher capacity for acidic proteins. Type II often provides superior selectivity and resolution in the separation of many proteins, particularly various species, subspecies, and classes of antibodies, as well as nucleic acids. The two types are often evaluated side by side to determine which material provides the maximum benefit in a given separation. Existing protocols that have been developed on crystalline hydroxyapatite can often be applied directly to the ceramic material with little or no modification. Table. Properties of CHT ceramic hydroxyapatite. Page 2: Mechanism of Action and Standard Ch Thank you, for helping us keep this platform clean. The editors will have a look at it as soon as possible. Lysozyme was used as a control to model cation exchange-dominant interactions. Bovine serum albumin was used as a control for calcium affinity-dominant interactions. Calcium affinity and phosphoryl cation exchange were positively cooperative for IgG-related species.

    0, loaded, washed, and eluted with a 20 CV linear gradient to 160 mM sodium phosphate, pH 7.0. It was then cleaned with 500 mM sodium phosphate, pH 7.0. A second experiment was run with 10 mM sodium chloride in both gradient buffers. Subsequent runs were conducted in the presence of 20, 40, 80, and 160 mM sodium chloride. Between experimental series, the column was stored in 20% ethanol, 10 mM sodium phosphate, pH 7.0. It is important to note that the conditions under which many of the above experiments were conducted may damage HA. Corresponding sodium chloride concentrations are presented in Table 1. Retentions of lysozyme and BSA are plotted in the same figure to represent the behavior of cation exchange-dominated and calcium affinity-dominated proteins. It failed to elute in sodium chloride gradients at phosphate concentrations up to 40 mM phosphate but failed to bind at 60 mM phosphate ( Fig. 2 ). Its steep response curve resembles the early part of the IgG curve. The 40 mM horizontal offset in phosphate concentration between the curves indicates that IgG has much lower calcium affinity than BSA. This would also be understood to limit the number of polycarboxyl domains configured appropriately to support coordination with HA calcium. It elutes in a sodium chloride gradient even in the absence of phosphate, and exhibits a shallow linear decline in retention as phosphate is added to the elution buffers. It resembles the latter portion of the IgG retention curve, except that retention of IgG is much stronger. Rituxan’s p I is slightly lower than lysozyme. This suggests that its stronger cation exchange binding reflects a larger number of interactions, consistent with the more than tenfold greater mass of IgG, but it could also indicate a cooperative contribution by calcium affinity. Open in a separate window Figure 2 Retention of IgG, BSA, and Lysozyme (Lys) as a function of conductivity in sodium chloride gradients at various phosphate concentrations (pH 7.0).

    The small triangles mark the inner perimeter of negatively charged oxygen molecules surrounding each surface calcium atom. The larger triangles mark the outer perimeter. Refer to the original reference for additional information and citations describing crystal structure. Phosphate elutes both primary retention mechanism; its high calcium affinity competes with calcium affinity interactions between HA and proteins; its conductivity weakens ion exchange interactions. Chloride acts primarily on ion exchange interactions; it has little effect on calcium affinity. The inherent limitation of these studies is that they have mostly been conducted for the purpose of aggregate removal, and the ranges of the key variables have been limited to practical operating ranges for HA. In the present study, we evaluate more extensive grids of phosphate gradients at different sodium chloride concentrations, and sodium chloride gradients at different phosphate concentrations in the hope of refining the model of IgG retention on HA. Immobilized papain and pepsin was obtained from Thermo Fisher Scientific, Rockford, IL, USA. A monoclonal antibody containing about 40% aggregates was a generous gift from Avid BioServices, Tustin, CA, USA. Briefly, the antibody and immobilized enzyme gel were equilibrated to the specified buffer. The immobilized enzyme was removed by centrifugation. The sample was eluted with a 20 column volume (CV) linear gradient to 20 mM Hepes, 1.0 M sodium chloride, pH 7.0. The column was cleaned with 500 mM sodium phosphate, pH 7.0. In the next experiment, the equilibration, wash, and elution buffers contained 5 mM sodium phosphate. In subsequent experiments, both buffers contained 10, 20, 40, 80, or 160 mM sodium phosphate. A corresponding series was conducted at pH 8.5, substituting 20 mM Tris for Hepes. Another series was developed by conducting phosphate gradients at different chloride concentrations. The column was equilibrated with 20 mM Hepes, pH 7.

    Eluting phosphate concentration and conductivity values for the above solutes plus Fc and Fab are presented in Table 2. Table 2 Elution phosphate concentration and conductivity at peak center in sodium phosphate gradients run at the indicated sodium chloride concentrations (pH 7.0) a) Solute Chloride concentration and conductivity increment during phosphate gradient. The lysozyme curve in Fig. 3 ascends at a much shallower angle than BSA and rapidly converges with the gradient start line. That it ascends at all illustrates a positive contribution by calcium affinity. If binding were exclusively electrostatic, the curve would be horizontal. Calcium affinity is weak, however, as illustrated by non-retention at 160 mM sodium chloride. Convergence of the lysozyme curve with the line marking conductivity at gradient start signifies loss of electrostatic binding with increasing chloride concentration. This is understood to represent cation exchange between HA phosphate and lysozyme amino residues. The slope of the IgG curve is essentially parallel with lysozyme at 80 mM sodium chloride, possibly reflecting its similar p I. The IgG slope diverged from lysozyme at 160 mM sodium chloride, becoming more positive, conforming more closely to the line marking conductivity at gradient start, and thereby revealing its stronger calcium affinity. The BSA and IgG curves in Fig. 3 exhibit depressed retention in the absence of sodium chloride. A similar phenomenon was observed for lysozyme in the absence of phosphate ( Fig. 2 ). These features suggest the influence of interactions that weaken retention. Weaker retention absent sodium chloride was attributed to restricted contact of DNA phosphates with HA calcium due to electrostatic repulsion between HA phosphates and DNA phosphates. Sodium chloride was believed to suppress this effect, allowing DNA to participate in more coordination events with HA calcium.

    Data points below the line of conductivity at gradient start indicate that the solute was unretained under the specified conditions. Elution chloride concentration and conductivity values are presented in Table 1. Refer to Section 2.2.2 for more detailed discussion of experimental conditions and to Sections 3.1 and 3.2 for discussion of the data. Table 1 Elution sodium chloride concentration and conductivity at peak center in sodium chloride gradients run at indicated phosphate concentrations (pH 7.0) a) Solute Phosphate concentration and conductivity increment during chloride gradient. NR indicates that it was not retained. NT indicates that it was not tested. Figure 3 plots retention of Rituxan, BSA, and lysozyme versus conductivity in phosphate gradients at different sodium chloride concentrations (pH 7.0). Corresponding phosphate concentrations are presented in Table 2. The figure exhibits the distinctive contributions of calcium affinity and cation exchange binding in a very different context, and reveals other influences. The most striking feature of the figure is that elution conductivities ascend with increasing sodium chloride concentration. This is unheard of with ion exchangers and highlights the conductivity resistance of calcium affinity, as exemplified by BSA. At sodium chloride concentrations greater than 10 mM, the BSA curve ascends nearly parallel with the line created by the conductivity at gradient start for the various experiments. This demonstrates virtual immunity to sodium chloride, which in turn indicates the weak contribution of electrostatic interactions. Open in a separate window Figure 3 Retention of IgG, Lysozyme, and BSA as a function of conductivity in sodium phosphate gradients at various sodium chloride concentrations (pH 7.0). Data points below the line marking conductivity at gradient start indicate that the solute was not retained under the specified conditions.

    This illustrates progressive loss of cation exchange binding while revealing a persistent contribution by calcium affinity. Refer to Section 2.2.2 for more detailed discussion of experimental conditions and to Section 3 for discussion of the data. Open in a separate window Figure 5 Retention of IgG, Fab, and Fc as a function of conductivity in sodium phosphate gradients at various sodium chloride concentrations (pH 7.0). Data points below the line marking conductivity at gradient start indicate that the solute was not retained under the specified conditions. Eluting phosphate concentration and conductivity values are presented in Table 2. Its larger size should also correspond to at least twice the number of binding interactions. The steeper slope of the Fc curve compared with IgG, and stronger binding than Fab in the absence of phosphate, suggest that Fc calcium affinity is intermediate between the two. Phosphoryl cation exchange for Fc was the weakest of all fragments: it failed to bind HA at 40 mM phosphate (5.9 mS). Data from phosphate gradients at different salt gradients support identical conclusions ( Fig. 5 ). Weaker Fc retention at all conductivities illustrates lower cation exchange binding, and the closer conformance of the slope with the line indicating conductivity at gradient start illustrates the relative dominance of calcium affinity. It makes sense that the cation exchange component of binding should be reduced since proteins generally become less electropositive with increasing pH. This would be expected to disproportionately reduce retention of solutes dominated by calcium affinity. Sodium chloride concentration and conductivity values are presented in Table 3. Refer to Section 2.2.2 for more detailed discussion of experimental conditions and to Section 3.2 for discussion of the data. Compound IgG-related structures exhibit the distinctive retention features of their components but bind more strongly.

    All examples suggest cooperativity, but most manifest too many confounding influences to express it with precision. Tetra-aggregates bound more strongly than IgG, by both calcium affinity and cation exchange, but not by a factor of 4 ( Fig. 7 ). This makes sense since associations among the individual IgG components must inevitably block some interactions with HA. This fits the definition for negative cooperativity. Open in a separate window Figure 7 Retention of IgG and aggregates as a function of conductivity in sodium chloride gradients at various phosphate concentrations (pH 7.0). The antibody was unretained at 160 mM phosphate. All other values are presented in Table 1. The lighter weight dashed line reproduces the curve for Rituxan from Fig. 2 for comparison. Refer to Section 2.2.2 for more detailed discussion of experimental conditions and to Sections 3.2 and 3.3 for discussion of the data. The p I s of IgG and its fragments provide no insight into the probability of either scenario. It is noted throughout the above discussion that various aspects of IgG and fragment retention are consistent with their p I s within an experimental series. This is not to suggest that p I is predictive of HA retention as a general matter. The greater the vertical offset between the elution conductivities for aggregated and non-aggregated antibody at a given phosphate concentration, the greater the separation. Figure 7 thus recommends that a sodium chloride gradient be applied at 5 mM phosphate. We evaluated aggregate separation in phosphate gradients at different salt concentrations but observed no separation under any conditions. All buffers can be made as dilutions of the 500 mM phosphate-cleaning buffer, and the elution conductivity of the antibody is usually low enough to support application to an ion exchanger with little more than moderate pH titration and dilution.

    BSA is far less charged than DNA but still heavily carboxylated, suggesting that its retention might also be depressed to some degree by repulsion from HA phosphates. The parallel low conductivity response of Rituxan equally suggests the effects of charge repulsion, but this conclusion is challenged by its low carboxylation relative to BSA. This could be the explanation, nevertheless. If the number of IgG carboxyls not involved in calcium affinity interactions were roughly similar to BSA, negative charge repulsion at low conductivity should also be similar. Rituxan’s high p I raises the possibility that the lower retention absent NaCl might reflect charge repulsion between HA calcium and IgG amino residues, but this is challenged by the behavior of lysozyme. First, lysozyme’s retention in Fig. 3 does not exhibit the low conductivity depression manifested by IgG. Second, lysozyme’s behavior in Fig. 2 points to a specific mechanism by which all kinds of electrostatic interactions with HA calcium might be eliminated. We suggest that similarly strong pairing between HA calcium and mobile phase phosphate ions eliminates electrostatic interactions involving HA calcium. Figure 2 suggests that 5 mM phosphate is sufficient to suspend electrostatic repulsion of lysozyme. If sufficient for lysozyme, it should be sufficient for IgG. Lysozyme fails to show the effect in Fig. 3 because it elutes far above that threshold, at about 85 mM phosphate ( Table 2 ). Note that this hypothesis also predicts that HA calcium should be incapable of electrostatically binding protein carboxyl residues in the presence of greater than 5 mM phosphate. Thus, it appears, in the presence of phosphate, that HA calcium is able to participate solely in coordination interactions. Ion exchange chromatography results were consistent with the above data and interpretations. Rituxan failed to bind to the anion exchanger at pH 7, which would have been predicted by its alkaline p I.

    It bound strongly to the cation exchanger at the same pH and eluted at 11.3 mS (135 mM sodium chloride). It bound to an HA column equilibrated at 10.4 mS (80 mM phosphate, Table 1 ), but failed to bind HA at 160 mM phosphate. This demonstrates reasonable conformance of cation exchange binding with HA when calcium affinity was quenched by phosphate. Overall, these data portray IgG retention on HA as embodying cation exchange retention roughly equivalent with dedicated cation exchangers, weak calcium affinity, very weak electrostatic repulsion between HA phosphate and IgG carboxyls, and no electrostatic interactions with HA calcium (in the presence of phosphate). Positive cooperativity between cation exchange and calcium affinity dominates retention. This interpretation, especially concerning cooperativity, is also consistent with published retention data in the form of dynamic binding capacity values. These data indicate much weaker calcium affinity than intact IgG, but comparison with retention on the cation exchanger demonstrates that cooperative enhancement by calcium affinity is still substantial. Even at 40 mM phosphate, sufficient calcium affinity remained to boost retention nearly threefold over the cation exchanger, to 17.2 mS. From 10 to 80 mM phosphate, the Fab retention curve essentially overlapped with the lysozyme curve (compare with Fig. 2 ), illustrating Fab’s dominant retention by cation exchange. The p I of Rituxan Fab was about 10, and its mass is only about 33% of intact IgG, both of which would be expected to reduce its retention compared with intact IgG, as shown. These observations are supported by the behavior of Fab in phosphate gradients at different chloride concentrations ( Table 2, Fig. 5 ). The early part of the Fab curve overlaps with lysozyme ( Fig. 3 ), illustrating cation exchange retention. With increasing sodium chloride concentrations, the curve becomes more parallel with the line indicating conductivity at gradient start.

    The high conductivities at which antibodies elute in chloride gradients requires that the HA step be placed at the end of the purification process, or that the eluate be buffer exchanged to permit compatibility with a subsequent ion exchange step. The phosphate-chloride grid approach may also be applied in purification process development for fragmentary constructs. As an example from Fig. 4, Fab and Fc co-elute in a sodium chloride gradient at 10 mM phosphate, but are well separated in a chloride gradient at 20 mM phosphate where Fc fails to bind. This approach may also be useful in the purification of recombinant constructs from cell culture media, where BSA is a frequent contaminant. In the event that BSA co-elutes with a given product in a phosphate gradient absent sodium chloride, addition of chloride will cause the construct to elute earlier while leaving BSA retention essentially unaltered ( Table 2 ). For any application, the phosphate-chloride grid approach provides a systematic characterization tool that can be used to support process validation. With sodium chloride gradients for example, the variation in the vertical offset between two contaminants over a specified range of phosphate concentration illustrates the sensitivity of the separation to variations within that range. Grid results can thus be used to document the quantitative response of the process to any pertinent variable, and to document that process specifications lie within a range where routine variations in such variables will not adversely affect process control. Both approaches represent a rational data-driven approach to process design and validation, and both should lead to the same conclusions. Robotic systems produce more data points per unit time, but with substantial overhead costs. The grid approach can be employed at lower cost and offers the advantage of being able to model flow rate-dependent variables such as capacity and resolution.

    Statistical design of experiments can be used to reduce the number of experiments for either approach, but results from the present study reveal an important caution: the effects of phosphate concentration are not linear over a broad range. A preliminary series of experiments should therefore be conducted to identify a narrow range of interest, within which design of experiments may be applied confidently. 4 Concluding remarks Results from this and other recent studies recommend several refinements to retention models that have been previously suggested for IgG. This documents that very weak calcium affinity interactions can be eluted exclusively by increasing conductivity, and suggests that stronger calcium affinity interactions are probably affected to some degree. Electrostatic repulsion between IgG carboxyls and HA phosphate occurs simultaneously with the dominant interactions of calcium affinity and phosphoryl cation exchange, but appears to be damped out at low conductivities and probably has a negligible effect on selectivity under typical elution conditions. All electrostatic interactions between protein charged residues and HA calcium are probably blocked by its strong complexation with mobile phase phosphate. While this model provides new insights concerning the interaction of IgG with HA, it remains far from complete and far from predictive. Many elements of HA interactivity with proteins remain inadequately characterized. Calcium affinity also requires more extensive characterization. Whether amino groups are also involved, including those in the peptide backbone, as in interactions between calcium and EDTA or EGTA, also remains to be determined. Hopefully, the substantial and growing economic importance of therapeutic antibodies, combined with the compelling abilities of HA for their purification, will encourage investigators to address these and other remaining questions. Acknowledgments Some parts of this research were supported by NCI grant CA43904.

    Abbreviations CV column volume HA hydroxyapatite MVM minute virus of mice MuLV murine leukemia virus Footnotes The authors have declared no conflict of interest. Bio-Rad Laboratories. Bigelow C, Channon M. Proteins. 3. Vol. 1. CRC Press; Boca Raton: 1976. Oral presentation. 12th Annual Waterside Conference; San Juan, Puerto Rico. Beam K, Wu H, Tsai P. Evaluation of ceramic hydroxyapatite for removal of a 50 kDa mAb fragment and process-related impurities, Oral presentation. 4th International Symposium on Hydroxyapatite; Sonoma. The minibody did not bind to protein A. Cation-exchange, anion-exchange, hydrophobic-interaction, and hydroxyapatite (eluted by phosphate gradient) chromatographic methods were scouted, but the minibody coeluted with BSA to a substantial degree on each. Hydroxyapatite eluted with a sodium chloride gradient separated BSA and also removed a dimeric contaminant, but BSA consumed so much binding capacity that this proved impractical as a capture tool. Capto MMC media proved capable of supporting adequate capture and significant dimer removal, although both loading and elution selectivity varied dramatically with the amount of supernatant applied to the column. An anion-exchange step was included to fortify overall virus and DNA removal. These results illustrate the value of multimodal chromatography methods when affinity chromatography methods are lacking and conventional alternatives prove inadequate. Keywords: Minibodies, multimodal chromatography methods, phase 1 purification, in vivo diagnostic imaging Small, genetically engineered immunological constructs are being developed industry-wide for a growing range of in vivo applications. Examples include Fab, F(ab')2, single-chain (sc) Fv, bis-scFV, diabodies, minibodies, and single-domain antibodies ( 1 ).

    Their small size potentially gives them access to tissues that are poorly accessible by intact antibodies; rapid clearance from blood and nontargeted tissues; lower immunogenic response; and eye-drop, inhalant, or oral administration. We report here on purification of an affinity-matured, humanized, antiprostate stem-cell antigen (PSCA) minibody for first-in-human clinical studies. This minibody and an earlier chimeric version have demonstrated excellent high-contrast microPET imaging for PSCA-positive human prostate, pancreatic, and bladder cancers in animal models ( Figure 1 ) ( 2 ). The overall structure is reminiscent of IgG, bivalent but only half the size. Although beneficial for effectiveness of the application, this architecture lacks the binding sites for protein A. Thus, the principal enabling tool for IgG platform purification is inapplicable, thereby presenting a greater challenge to process developers. Tumor locations are indicated by yellow arrows. Response scale is red (high) to blue (low). Open in a separate window Figure 2 Structural comparison of a human IgG1 and an anti-PSCA minibody; references 2, 28, and 29 provide more information about the minibody's development, structure, characterization, and applications. Multimodal (mixed-mode) chromatography methods have existed since the 1950s ( 3 ). Hydroxyapatite (HA) is the archetype of multimodal chromatography methods, combining cation exchange and metal affinity. ( 4 ). It is also a prime example of the barriers that need to be overcome for mixed modes to become mainstream tools. HA's selectivity was recognized as unique from its introduction, but a lack of practical knowledge concerning its binding mechanisms long delayed the development of scouting pathways that fully revealed its abilities. That discouraged process developers who might have benefited from its capabilities. Successes in recombinant immunotherapy have stimulated introduction of other mixed-mode media.

    Charged-hydrophobic mixed modes began to appear in the 1980s, mostly as hopeful protein A replacements. Such products arrive at a propitious moment: HA's successes have made process developers willing to confront the complexity of mixed modes and provided a conceptual framework for exploring multimodal interactions. High-throughput screening and statistical design of experiments (DoE) enable rapid accumulation of process-pertinent data ( 7, 25, 26 ). And the well-defined chemical structures of mixed-mode ligands provide valuable guidance on the types of eluting agents that promise useful results ( 27 ). Materials and Methods Cell Culture Anti-PSCA minibody (clone A11.1 2C3) was grown in NS0 cells using media supplemented with 2% fetal bovine serum. It is effective even at physiological pH and conductivity levels, at which its affinity for IgG and minibodies is nil. Used media can be discarded. We used 20 mM MES for buffering at pH 6, 20 mM Hepes at pH 7, and 20 mM Tris at pH 8. CX experiments (pH 4.5) were conducted in 20 mM sodium acetate. For an initial scouting run, the column was equilibrated to 10 mM sodium phosphate at pH 6.5, eluted in a linear gradient to 250 mM phosphate, and cleaned with 500 mM phosphate. A second run was conducted by equilibrating to 20 mM sodium phosphate at pH 6.5, eluting with a linear gradient to 20 mM phosphate and 1 M NaCl, then cleaning with 500 mM phosphate. Sample was prepared by 1:1 dilution of CCS with 50 mM MES at pH 6.0. The column was equilibrated with the same buffer, eluted with a linear gradient to 50 mM MES and 500 mM arginine, then cleaned with 2 M guanidine at pH 5.5. We used the higher MES concentration to compensate for buffer capacity of the MMC carboxyl group. Analysis We ran reduced and nonreduced sodium-dodecyl-sulfate polyacrylamide gel electrophoresis (SDS-PAGE) on precast Ready Gel 10% Tris-HCl Ready gels from Bio-Rad. Results and Discussion First-pass scouting results were revealing but disappointing.


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    This DownloadabThanks for takThanks for taking the time to look at this Complete Service ReFixing problems in your vehicle is a do-it-approach with the Auto Repair Manuals as they contain comprehensive inThanks for taking the time to look at this Complete Service Repair Workshop Manual. This Downloadable Manual coverThanks for taking the time to look at this Complete Service Repair Workshop Manual. This Downloadable Manual coverAll diagnostic and repair procedures are cAll diagnostic and repair procedures are cAll diagnostic and repair procedures are cAll diagnostic and repair procedures are cAll diagnostic and repair procedures are cNo Extra fees, No Expiry dates. It may have been moved, or removed altogether. Perhaps you can return back to the site's homepage and see if you can find what you are looking for. The general director is Sergio Marchionne (at the same time he is the chief executive ofElectronic and aerospace products are produced. Headquartered in Auburn Hills. Try refining your search, or use the navigation above to locate the post. Klaus Mey on Rail Trails of the West Kootenays Archives. And by having access to our ebooks online or by storing it on your computer, you have convenient answers with Workshop Manual Chrysler 8d. To get started finding Workshop Manual Chrysler 8d, you are right to find our website which has a comprehensive collection of manuals listed. Our library is the biggest of these that have literally hundreds of thousands of different products represented. I get my most wanted eBook Many thanks If there is a survey it only takes 5 minutes, try any survey which works for you. All Chrysler 300 repair manuals are in pdf format for easy download. No special software required to download a manual. You can save the manual to your downloads folder or desktop forever. The manual is nothing more than a repair manual in printed form that has been scanned and converted into digital form so as to be processed and viewed on a computer.

    These repair manuals are the ultimate do-it-yourself instructional books. They were written by a team of automotive engineers and based on a complete teardown and rebuild of the entire motor vehicle. The manuals explain diagnosis and testing procedures, part removal and installation, component inspection and testing, disassembly and assembly and gives a complete description of each part. You can literally use the manual disassemble the entire vehicle and put it back together again. Dodge Charger and Dodge Magnum models are also covered in these manuals. The books contain thousands of pictures, diagrams, schematics an illustration that will ensure any newbie mechanic completes the repair work successfully. And by having access to our ebooks online or by storing it on your computer, you have convenient answers with Daewoo Matiz Workshop Manual Free. To get started finding Daewoo Matiz Workshop Manual Free, you are right to find our website which has a comprehensive collection of manuals listed. Our library is the biggest of these that have literally hundreds of thousands of different products represented. I get my most wanted eBook Many thanks If there is a survey it only takes 5 minutes, try any survey which works for you. For a more clear look, you may open some examples below. All of the good examples about Chrysler Workshop Manual Free Download about this web site, we get from many sources so you could create a better document of your own. When the search you acquire here does not complement what you are seeking for, please make use of the research feature that we have provided here. You will be free to download something that we provide here, investment decision you won't cost you the particular slightest. Please upgrade your browser to improve your experience. The Chrysler Valiant was a passenger car which was introduced by Chrysler Australia in 1962 with production ceasing in 1981.

    It was officially unveiled by South Australia's Premier, Sir Thomas Playford, in January 1962. The RV1 (or R Series) Valiant was an instant success. Not everyone was taken instantly by the car's styling, but the general consensus, was that the car had a modern, almost space age quality about it. The most successful drivers were Leo Leonard and Jim Little, who still races his Valiants (mostly pre-65 class).My email address is: What for? Understood. And by having access to our ebooks online or by storing it on your computer, you have convenient answers with Chrysler Repair Manual Free. To get started finding Chrysler Repair Manual Free, you are right to find our website which has a comprehensive collection of manuals listed. Our library is the biggest of these that have literally hundreds of thousands of different products represented. I get my most wanted eBook Many thanks If there is a survey it only takes 5 minutes, try any survey which works for you.


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    It takes longer than you expect to install, if you want to install it right. Depending on your experience 30 minutes to an hour. The instructions call for the double pole 50 amp circuit breaker to be installed close as to the main breaker as possible. In our case we had to move two single pole 20 amp Breakers down which go to Kitchen GFI. And use those positions to install the 50 amp breaker next to the main breaker. Using Pliers broke out two filler tabs for the 20 amp breakers moved down. Instructions also calls for a liquid tight connection to box but there is no gasket included to make a liquid tight connection. If your breaker panel is indoors and there are no water pipes near the panel, you may be able to install it without a liquid tight connection. Or use a silicone RTV gasket sealant to seal the unit tight to the exterior of the panel box. This was the option we chose. And we mounted the unit at the bottom of the box to protect it from the rain and weather. Used a good sized bead so that the RTV squeezed out and into the inside of box completely sealing unit to box. Used hammer and the flat blade screwdriver to knock out the plug at the bottom nearest to the back and pliers to pull it off. Sometimes there is a burr that is left and it will need to be filed smooth. The wires supplied on the unit are about 18 inches long (45 cm) so we had to lengthen the red and black wires to reach to the 50 Amp Breaker at the top near the main breaker. Although the unit comes with 14 AWG stranded wires up sized to 12 AWG wire to reduce resistance. Do not use automotive grade 14 gauge stranded the insulation is not rated for AC voltage. We striped the wires and used yellow wire nuts that make the connections to the added wire. Then for additional safety wrapped electrical tape in the same direction we turned the nuts. Then fold it over the nut on to the wire and taped over for additional safety. Now house is fully protected against surges.

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    Please enter another search term. They provide premium surge protection for AC power and cable at the point of entrance to the home. Protection at this location can reduce surges entering the home to an acceptable level for your home electronics and appliances.All Rights Reserved. Our payment security system encrypts your information during transmission. We don’t share your credit card details with third-party sellers, and we don’t sell your information to others. Please try again.Please try again.Show details. Ships from and sold by Amazon.com. In order to navigate out of this carousel please use your heading shortcut key to navigate to the next or previous heading. Register a free business account Please try your search again later.Quick connect design—easy to mount telephone and cable protection modules. LED status indication. Type 2 AC Power protection.To calculate the overall star rating and percentage breakdown by star, we don’t use a simple average. Instead, our system considers things like how recent a review is and if the reviewer bought the item on Amazon. It also analyzes reviews to verify trustworthiness. Please try again later. S Kennedy 2.0 out of 5 stars And a GFI and the kitchen failed. It's important to connect the surge protector as close as possible to where the ground and neutral enter the bus bars. Will need the following materials and tools to install properly if your breaker box is vertical and mounting unit at bottom of box. 50 Amp double pole circuit breaker to match your breaker panel (called for in instructions). One each Red, Black, Green and White 12 AWG stranded wire 2 to 3 feet (60 - 90 cm) long each. May be shorter or longer depending on your panel and mounting location. 4 wire Nuts (Yellow). Electrical tape (optional) Wire strippers. Flat Blade screw driver. Hammer Pliers Small round file to remove burrs. RTV or Silicon Gasket Material. Especially if Breaker box is part of the service entrance and is outside. Ours is outside.

    I installed it flush to my electrical panel using one of the free knock-outs. Installation took all of about 15 minutes from beginning to end. You will have to purchase a double-poled 50 amp breaker which was about 10.00. Wiring is very straight forward however a word of caution. If you are not familiar with working inside of an electrical panel, DO NOT try to install this yourself. You can easily kill yourself working inside of an electrical panel if you are not sure what you are doing. I am very happy with the purchase and recommend it to anyone. I will update this review should this ever get used to stop a surge. Hopefully I will never have to find out if it works!Purchased a Siemens 50 amp double-pole breaker (you will need to purchase a breaker that is compatible with your own load center). Installation was very easy. Shut off power at the main breaker inside the load center. Flipped the 50 amp breaker off before installing. Installed 50 amp breaker onto bus bar. Mounted Eaton surge protector (how you mount it will vary based on how one’s load center is configured). Connected green wire to ground bar, white (neutral) wire to neutral bar, red wire to one of the 50-amp breakers, and the black wire to the other 50-amp breaker. Checked all wiring. Flipped the main breaker on. Flipped the 50 amp breaker on. Everything is good. LED lights on the surge protector are both on. As always, if you are not familiar with electricity and installing electrical components, please hire a certified electrician.I was unable to properly secure the 14 AWG wires to the 50 ampere circuit breaker because wire gauge was too small for the breaker terminal screws which are designed for 6 AWG wiring. I had to tin the two wires and make a solder loop to increase the size of the wires that would allow me to secure properly them to the 50 ampere circuit breaker terminals. Can a 14 AWG wire be installed using a 50 ampere circuit breaker? Yes. The connecting wires do not carry load current.

    But still will use 120V surge protection strips to provide additional protection for electronic devices. Added this unit to protect the electronic controls on our new dryer and our induction range. But it also provides protection till the refrigerator, microwave and air fry oven which all have electronic control boards and adding a hundred twenty volt surge protector is not easily done. The reason down grades to 4 stars is because the wire length is too short and had to add on to make it work in this application and they did not provide a gasket which are available from McMaster-Carr and are intended for a 1 inch hose washer. Wasn't about to buy 100 pieces for one installation and pay shipping. If you have everything on hand it will take you about 30 minutes to one hour to install it. But because we had to run back to the store to get additional wire it took us 2 hours. It's better to buy a little more wire and cut off the excess then to have to go to the store again. Saw the surge protector in action. A surge came from the Utility side (this is why you connected closest to the main) and the surge protector acted immediately and shunted the surge to ground. Lights did not dim appreciably but didn't notice our computers and TVs turn off just for a second then turn back on. The surge protector work the way it was supposed to. When it's shunted the surge to ground there was a temporary loss of power, but once the search had passed. The Protector returned back to normal mode.And my son's computer did a check to make sure everything was running okay. We also have standby power supplies with surge protection on our computers. That extra effort to install it correctly protected all our electronics and the new washer and dryer we just purchased.Easy to install ( I'm electrician) unless you’re an electrician, or have previous experience working with electric panels and know what the heck you’re doing, I highly recommend hiring an electrician for this job.

    I've layered them with both protection at the panel (type 2) and at the plug (type 3) - its the most I can do. Fingers Crossed!Sorry, we failed to record your vote. Please try again I found it easy to install. Hard to say how well it works until there's an actual incident where it's required.Sorry, we failed to record your vote. Please try again Sorry, we failed to record your vote. Please try again I am very happy that I now have peace of mind for all of my devices that are not already surge protected. I will recommend this to anyone and everyone I talk to.Sorry, we failed to record your vote. Please try again I have to just assume it's going to do the job if it ever gets put to the test.Sorry, we failed to record your vote. Please try again My electrician was ready to put this on a 15-amp, single-pole circuit which is fine, but in the instructions it states that to get the maximum amount of protection from the device, it needs to be on a 2-pole, 50A circuit.Sorry, we failed to record your vote. Please try again By changing weather and more thunderstorms in our area, we decided to installed surge protection on main fuse box to protect all electronic devices in case of power outage.Sorry, we failed to record your vote. Please try again The price is a little high for something that I’m not sure will work but I guess it’s nice to have peace of mind.Sorry, we failed to record your vote. Please try again In order to navigate out of this carousel please use your heading shortcut key to navigate to the next or previous heading. We are committed to doing everything we can to ship your package as soon as possible. For more information please visit our FAQ page below. COVID FAQs. The item may be missing the original packaging, or in the original packaging but not sealed. The item may be a factory Surplus. Brand: Cutler-Hammer Model: CPS100480YAK Type: Surge Protective Device SPW Industrial warrants this.

    Instead, they carry only short-duration currents that are associated with a transient event.Sorry, we failed to record your vote. Please try again Looking through all the reviews online, this model comes as the best overall deal, and it's universal since it connects to any 50A breaker. The install is very simple. 2 wires into a dual pole breaker, 1 wire to ground, 1 wire to neutral. The breaker, while others recommend placing as close to the main in line, can go anywhere in the panel. Surges will always look for the shortest way to ground, so it's unlikely you have anything closer than the surge protector. It's more important to keep the wires from the protector as short and kink free as possible. The 2 green LEDs ensure it's easy to check if the protector needs to be replaced. Only time will tell how effective it is, but with the 108kA rating, it gives some peace of mind.Sorry, we failed to record your vote. Please try again Wires were too short to mount below my my 200amp panel and reach up to a 2 pole breaker at top of panel as recommended. I just installed a rectangular junction box between the panel and surge protector. May never know if it does its job unless the indicator lights go out or it fries with power still working in the house.Sorry, we failed to record your vote. Please try again A good idea if you live in a rural area and are subject to power outages. The current spikes can damage electronic equipment, including stoves, fridges, and microwaves, and this helps to eliminate them.Sorry, we failed to record your vote. Please try again I did get the proper 50 amp 2 pole breaker for my panel as outlined in manual which is probably important if you are purchasing one.Sorry, we failed to record your vote. Please try again I'd done my research, so knew what to expect and wasn't disappointed. Installation was quick and easy. Now we have some satisfaction that our sensitive home appliances and electronics are protected from nasty surges.

    Choose from a wide selection of desktop computers and essential hardware to create an efficient experience from the comfort of your home. Whether you need a new laptop for work or building a powerful home theater system, you'll be on the cutting edge of technology with electronics from Sears. All Rights Reserved Connect with us: shop your way Facebook Twitter Google Plus Instagram. Something went wrong. Please message us with what you want to buy and we will see if we can find it for you. Green Mountain Liquidators 86 followers greenmountainliquidators ( 4134 greenmountainliquidators's Feedback score is 4134 ) 100.0% greenmountainliquidators has 100% positive Feedback We are still shipping daily Monday-Friday (as long as the USPS and UPS are still open) during the Covid-19 situation. Please message us to find out the latest shipping time and if there are any delays. Thank You and stay safe everyone!! Save this seller Contact seller Side Refine Panel Category All 0 results shown in all categories User Agreement, Privacy, Cookies and AdChoice Norton Secured - powered by Verisign. Centro de Carga Electrico para la proteccion del hogar: El servicio de entrada; centro de carga o base de medidor y switch son puntos excelentes.Los protectores de voltaje son dispositivos Ahorrador de Electricidad Industrial Trifasico, es perfecto para pequenos y medianos Modelo: MAGI60 El mejor ahorrador para los grandes consumidores semi industriales. Ahorrador de Electricidad Industrial Trifasico, es perfecto para pequenos y medianos Las tarifas aplican exclusivamente para la compra de los servicios Radio, TV y otros aparatos electricos Cuando salgas de vacaciones, desconecta tus aparatos electricos, ya que algunos Siena Inmobiliaria se adelanta al futuro desarrollando Ahorro y uso. eficiente de energia Y nos encanta! En IIS Latam, creemos que tener Una guia para los propietarios de viviendas Y Cables para ambas de 5 mts.

    En primer lugar tenemos la DVR, grabadora de video digital, es el lugar donde se Absolutamente! Absolutamente! Que es un sistema de cine en casa. Un sistema de cine en casa reproduce una experiencia similar al cine en el hogar, con comodidad y segun su conveniencia. Un panel solar produce electricidad cuando hay luz. Mientras mas sol hay, mas electricidad se generara. La maxima generacion se produce en verano a mediodia. Las tarifas aplican exclusivamente para la compra de los servicios de La tecnologia del futuro hoy!! La tecnologia del futuro hoy!! Energizadores SmartPower MBX son fuertes y fiables. El avanzado MBX adapta su salida a las condiciones No obstante ello, para Usos: domestico y comerciales limpieza, Apreciado Usuario El presente manual tiene como objetivo brindarle la informacion necesaria Apreciado usuario: El presente manual tiene como objetivo brindarle la informacion Si los sistemas de la vivienda Las memorias USB son el regalo promocional perfecto. Se agradecen Programa de Educacion Financiera FanCooler: Tambien conocidos como Electro T8 120cm -18W Alta Calidad YAPI LED s Para Haztuparteporelmedio ambienteysaldrasganando: Reducestusconsumosdomesticos.Instalar un jack RJ-45 en una placa de pared. Utilizar El plan energetico horizonte 2010 preve diferentes actuaciones para fomentar el ahorrro y la eficiencia energetica. Estas actuaciones Proceso de recarga simplificado Detras de la tecnologia e-tron de Audi hay un principio simple: conectar y recargar. Asi, recargar Porque: Producen electricidad a partir de una fuente de energia limpia Puede recibir un dinero por la produccion Produccion y Siniestros. 5. Charla con aseguradores. Gran confort en a.c.s. Confort para la vida Descodificador Telefonica -3800TW Como funciona una cerca electrica Debido a esto, tu necesitas: El cercado electrico ofrece mas ventajas que el cercado convencional. En primer lugar es mas economico ( un 50% menos) en terminos de material y trabajo.

    Average delivery time is 1 to 2 days delivery may vary depending on product availability. Same.The item may have some signs of cosmetic wear, but is fully operational and functions as intended. Notes:.Average delivery time is 1 to 2 days delivery may vary depending on product availability. Same.The item may be missing the original packaging, or in the original packaging but not sealed. The item.The item may be missing the original packaging, or in the original packaging but not sealed. The item.Brand: WESWOX MPN: WESWOXBrand: Westinghouse MPN: 591C142G07 Model: CLS-15 Country of Manufacture:.This means the item has been inspected, cleaned,.Condition: Used United States. Manufacturer. Purcell. Please refer to the specific WARNING and CAUTION in Section before pro-ceeding. FOLLOW PROPER INSTALLATION, OPERATION, AND MAIN-TENANCE PROCEDURES TO AVOID THESE Transfer switch equipment COVERED BY THIS INSTRUC-TION BOOK IS DESIGNED AND TESTED TO OPERATE WITHIN ITS NAMEPLATE RATINGS. ALL RESPON-SIBLE PERSONNEL SHOULD LOCATE THE DOOR MOUNTED equipment NAMEPLATE AND BE FAMILIAR WITH THE INFORMA-TION PROVIDED ON THE NAMEPLATE. 5 A TYPICAL equipment NAMEPLATE IS SHOWN IN FIGURE WARNINGS AND CAUTIONS INCLUDED AS PART OF THE PRO-CEDURAL STEPS IN THIS DOCUMENT ARE FOR PERSONAL SAFETY AND PROTECTION OF equipment FROM DAMAGE.IN ADDITION, ONLY QUALIFIED PERSONS SHOULD BE PERMITTED TO PERFORM ANY WORK ASSOCIATED WITH THE equipment. 6 ANY WIRING INSTRUCTIONS PRESENTED IN THIS DOCUMENT MUST BE FOL-LOWED PRECISELY. The load s utility (Source 1) power source is backed up by a generator (Source 2) power source. An ATS is connected to both the utility and generator power sources and supplies the load with power from one of these two sources. In the event that power is lost from the utility power source, the ATS transfers the load to the generator power source. 7 Once the utility power is restored, the load is automatically transferred back to the utility power source (Figure 2).Figure 2.

    Typical Load Transfer switch (Contactor) intelligence system initiates the Transfer when the utility power source fails or falls below a preset voltage. An engine start is then initiated and the ATS transfers to the generator power source when sufficient generator voltage is available. When the utility power source is restored, the ATS automatically transfers back and the generator will shut down after a time delay. In addition, a Manual over-ride lever is provided for the Transfer 3. CHGEN ATS (100 A). Optional Service Entrance FeatureThe ATS can be ordered in either a standard or service entrance (SE) configuration. When ordered as an SE, integral overcurrent protection is built into the switch. Therefore, the ATS can be installed at the point of service entrance without the need for an upstream disconnect device. Free shipping for many products. C wire is required and is the power source. Pinterest Explore Log in Sign up Privacy. A desktop computer or laptop puts users in direct contact with other people across the Internet for collaborative work projects or to keep up with long-distance friends and family. Tablets are great for on-the-go entertainment like eBooks, music and movies, while advanced wristbands and smart watches can even help keep track working out on different exercise equipment. From flat screen TVs to portable music devices, Sears carries a wide selection of consumer electronics for you. Smart lighting, thermostats and other appliances use Connected Solutions automation, which makes it possible to control parts of your home. Close the garage door from the office with a remote garage door opener, or use digital keys to open smart locks around your home. Wireless home surveillance systems send video directly to a smartphone or tablet using a Wi-Fi or cellular connection, giving you peace of mind that your home is secure no matter where you are. An office requires high-quality equipment.

    Existen tecnicas para obtener importantes ahorros de energia. Las fundamentales son: Cogeneracion. Generacion Material Figura 1: Montaje de la practica de introduccion al osciloscopio. 1 Professionals Serving Professionals Soporte universal para telefono movil y adaptador de carga USB FECHA: 2009 1. OBJETIVOS 1.1. El objetivo es definir una proteccion Proteccion contra Transientes de Sobrevoltaje TABLA DE CONTENIDOS 3 Antes de Empezar 6 Especificaciones tecnicas 8 Caracteristicas Confiable Accesible Rapido Compatible Sin embargo, debido al desarrollo continuo de las diferentes estructuras de edificios Es cierto que por sobre todas las cosas somos una casa de empeno, pero tambien somos competencia Por ejemplo, To use this website, you must agree to our Privacy Policy, including cookie policy. Page Count: 120 Raleigh, NC 27615 U.S.A. Toll Free: 1.800.356.5794Eaton, Powerware, ABM, Ferrups. BladeUPS, Power Xpert, PowerTrust. PowerTrust Preferred, LanSafe, X-Slot. Sync, PowerVision, and PowerChain. Management are trade names. Eaton Corporation or its subsidiariesAll Rights Reserved. Printed in USAMay 11, 2008). MGE Office Protection Systems product pricingThe move resulted inMoving forward in 2008, we are in the process of realizing a unifiedAs such, we have developed a price book supplementIntroduction. Restriction of Hazardous Substances Directive. 3. Risk Protection as Easy as 3, 5, 9. 4Which UPS is Right for Your Customer?.. 6. What’s the Harm in Harmonics?. 8. Series 9 and Ferro UPSs Address Harmonics.. 9. Single-phase Powerware Product Warranty Overview. 10. Ordering Information, Parts, Accessories and Current List Pricing. Powerware Data Center SolutionsPowerware Environmental Rack Monitor (ERM). 16. Powerware Remote Power Panel (RPP). 17. UL Listed Power Distribution Cables.19. Series 3 Single-phase (Standby)Series 5 Single-phase (Line-interactive)Powerware 5115 Tower. Powerware 5115 Rack. Powerware 5125 Tower.Powerware Extended Power Distribution Module (EPDM).

    38. Powerware 9140.. 39. Powerware 9155. 41. Series FERROSeries 9 Three-phase (Online)Ordering Information, Parts, Accessories and Current List Pricing (continued). Additional Products and ServicesConnectivity Products.. 69. Residential Surge Products. 73. Portable Generators.. 75Powerware Product Services. 83. Single-phase Service Plans.. 88. Three-phase Service Plans.96. Powerware Three-phase UPS Batteries..101. Input Plug and Output Receptacle Chart. 102. Sales Returned Merchandise Authorization (RMA) Policy.. 103Note: Due to continuing product improvement programs, all specifications and prices are subject to change without notice. Note: With the exception of batteries, any UPS parts or parts kit pricing that is included in this price book is based on a concurrent purchase of a new unit(s). Pricing for parts or parts kitsEaton is committed to setting higher standards for the environment by demanding higher standards for ourThe Powerware BladeUPS offers UPS power protection for blade servers with an industry-leading efficiency. Powerware EPDUs are equipped withSometimes, the more fiscally responsible option is also the most environmentally sound. Commit to a GREENERRoHS. Restriction of Hazardous Substances Directive. The Restriction of Hazardous Substances Directive (RoHS)This directiveRoHS restricts the use of the following six substances:Visit www.powerware.com for updated RoHS compliance information.You've invested thousands in the best equipment. You consider your data a priceless commodity. So much is at stake when it comes to yourFrom power failures and surges to premature hardware failure,These power problems are potentially devastating to your data and computer hardware, and not every UPS protects against them all.

    Eaton’sOnly Powerware UPSs incorporate the simple and unique 3, 5, 9 selection system, allowing you to easily determine which solution best meetsEaton offers a comprehensive selection of Powerware UPS solutions based on protecting against the nine most common power threats,Our single-phase offering caters to the needs of the smallest home offices, extending toIf you are seeking advanced protection to encompass large-scalePowerware Series 3 UPS. Primarily protects your systems against three of the nine powerThis basic level of protection is necessary to prevent damages toData loss. File corruption. Flickering lights. Hardware damage. Equipment shutoff. The Powerware Series 3 UPS is ideal for standalone and networkedPowerware Series 5 UPS. Most effective against five of the nine power threats to yourPower failures. Power sags. Power surges. Under-voltage. Over-voltage. Powerware Series 5 UPSs safeguard your equipment from all of thePremature hardware failure. Data loss and corruption. Data error. Keyboard lockup. Storage loss. System lockup. Powerware Series 5 UPSs are ideal for use with workstations,Powerware Series 9 UPS. Comprehensive protects your data and equipment against all ninePower failures. Line noise. Switching transients. Frequency variation. Harmonic distortion. The Powerware Series 9 UPS delivers full protection for your criticalUPSs, as well as. Component stress. Burned circuit boards. Data crashes. Program failures. Powerware Series 9 UPSs deliver the ideal level of protection forProviding you with the most comprehensive level of protection,Storage Area Network (SAN) systems, IP telephony (VoIP), and rackPower SagLine NoiseVariation. Solution. A total loss of utility power.

    Can be caused by a number of events: Triggered by the startup of large loads, In addition to crashes, Can be caused by a lightning strike and Increased line voltage Triggered by a rapid reduction in powerThe results canEMI interference Normal duration is shorter than a spikeSwitching. Transient. Harmonic. DistortionSingle-phase Series 3 UPS. Power Problem. Switch mode power supplies, variableOur approach to power protection revolves around the nine mostSeries 3 UPS. There are three types of UPS: Series 3, Series 5, and Series 9. ToIt is obvious that the idealBut there may be applications where theVTHD in 9%. What the Experts Say. The Series 3 UPS offers a low-price solution to environments requiringUtility power is provided during normalVTHD Out 9%. Series 5 UPS. Institute of Electrical and Electronic Engineers (IEEE). Power equipment is susceptible to mis-operation caused by harmonicTable 3.3.1 for systems operating at less than 69 kV: less than 5.0%Series 5 UPSs provide basic power protection at mid range prices. Line-interactive UPSs provide more voltage regulation than off-line. Harmonic distortion, however, passes through unaffected. VTHD in 9%. VTHD Out 9%. Series 9 UPS. Series 9 UPSs are ideally suited to protect critical equipment. Online. UPSs protect against all types of power problems and continuouslyPowerware Series 9 UPSs isolate equipment from harmonic distortionVTHD in 9%. VTHD Out Source Exif Data: File Type: PDF. File Type Extension: pdf. PDF Version: 1.3. Linearized: Yes. Tagged PDF: No. XMP Toolkit: 3.1-701. About: 054d5957-f9a7-11da-82f9-b05aa80def59. Metadata Date: 2008:04:17 08:19:06-05:00. Modify Date: 2008:04:17 08:19:06-05:00. Creator Tool: Adobe InDesign CS2 (4.0.5). Thumbnail Format: JPEG. Thumbnail Width: 256. Thumbnail Height: 256. Thumbnail Image: (Binary data 8261 bytes, use -b option to extract). Instance ID: uuid:cd292a89-2c77-485f-8ba9-da5184a7aade. Document ID: adobe:docid:indd:3af0f6c0-a963-11dc-bd08-b0bdca25fe7c.

    Rendition Class: proof:pdf. Derived From Instance ID: 3af0f6bf-a963-11dc-bd08-b0bdca25fe7c. Derived From Document ID: adobe:docid:indd:29e672d5-a64b-11dc-99ff-9e28e1b4d4ae. Producer: Adobe PDF Library 7.0. Trapped: False. Has XFA: No. Page Count: 120. Creator: Adobe InDesign CS2 (4.0.5).


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